Design Principles and Self-Assembling Properties of a Plant Extracellular Interactome

演題

Design Principles and Self-Assembling Properties of a Plant Extracellular Interactome

講演者

Youssef Belkhadir,PhD (Group Leader, GMI-Gregor Mendel Institute, Austria)

使用言語

English

日時

2016年11月28日(月曜日) 15：00～16：30

場所

大セミナー室

内容

An expanded family of related cell surface receptor kinases (RKs) (greater than 400 predicted in the Arabidopsis genome) transduce either ‘self’ or ‘non‐self’derived signals into changes in nuclear gene expression. Plant RKs are typically characterized by an extracellular domain, a single transmembrane pass and in most cases, a functional intracellular kinase domain. Extracellular domains (ECDs) can modulate the assembly of signaling competent RKs complexes by controlling ligand specificity and recruiting appropriate signaling partners. Owing to the inherently transient nature of their interactions and bottlenecks with their expression in heterologous systems, there is very limited knowledge on the global interaction network ECDs can constitute in their resting or ligand-activated functioning modes. We will present our genome-scale efforts aimed at discovering novel ECD interactions in the RKs repertoire of Arabidopsis

問合せ先

植物免疫学
西條 雄介 (saijo@bs.naist.jp)